血浆同型半胱氨酸的含量与中青年脑梗死之间关系的探讨

被引:3
作者
付璐
辛晓敏
李洁
杜柏岩
关秀茹
赵庆杰
机构
[1] 哈尔滨医科大学第一临床医学院实验诊断教研室
关键词
中青年; 脑梗死; 同型半胱氨酸; 高血压; 雌激素;
D O I
暂无
中图分类号
R743.33 [脑栓塞];
学科分类号
摘要
目的 探讨血浆同型半胱氨酸的含量与中青年脑梗死之间的关系以及血浆同型半胱氨酸浓度的影响因素。方法 检测 4 0例中青年脑梗死患者的血浆同型半胱氨酸 (hcy)的浓度 ;正常对照组 4 0例。结果 青年脑梗死患者血浆hcy高于青年对照组 (P <0 .0 5 ) ,中年脑梗死患者血浆hcy高于中年对照组 ,青年脑梗死患者血浆hcy高于中年脑梗死患者 (P <0 .0 5 )。在中年组男女之间hcy的差异具有显著性 (P <0 .0 5 )。青中年两组中高血压性脑梗死患者的hcy水平均高于同年龄组单纯脑梗死患者 (P <0 .0 5 )。结论 hcy确实是脑梗死的一个重要发病因素 ,并且hcy对青年脑梗死的影响要大于中年人。雌激素水平对血浆hcy也有影响 ,高hcy血症与高血压性脑梗死有关
引用
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页码:390 / 392
页数:3
相关论文
共 7 条
  • [1] Hyperhomocysteinemia: a new risk factor for many kinds of diseases: summary for national symposiumon hyperhomocysteinemia and disease. Gao W,Tang J. Chinese Medical Journal . 1999
  • [2] Plasma homocysteine before and after methionine loading with regard to age, gender and menopausal stautus. Andersson A,Brattstrom L,Israelsson B,et al. European Journal of Clinical Investigation . 1992
  • [3] Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and stroke risk factors. Brattstrom L,Lindgren A,Israelsson B,et al. European Journal of Clinical Investigation . 1992
  • [4] Prospective study of serum homocysteine concentration and risk of stroke in middle-aged British men. Perry IJ,Refsum H,Morris RW,et al. The Lancet . 1995
  • [5] Vascular pathology of homocysteine: implications of the pathogenesis of arteriosclerosis. McCully KS. American Journal of Pathology . 1969
  • [6] Homocysteine and ischaemic stroke in men: the Caerphilly study. Fallon UB,Elwood P,Ben-Shlomo Y,et al. Journal of Epidemiology and Community Health . 2001
  • [7] Long-term effects of oral and transdermal hormone replacement therapy on plasma homocysteine levels. Chiantera V,Sarti CD,Fornaro F,et al. Menopause . 2003