抗菌药物治疗细菌性阴道炎预防早产的临床分析

被引：2

作者：

沈正泽 ^{[1
]}

金梅 ^{[1
]}

秧茂盛 ^{[2
,3
]}

机构：

[1] 重庆医科大学附属永川医院

[2] 重庆医科大学药学院

[3] 吉首大学医学院

来源：

华西药学杂志 | 2015年 / 30卷 / 01期

关键词：

早产; 抗菌药物; 细菌性阴道炎; 随机对照试验; Meta分析;

D O I：

10.13375/j.cnki.wcjps.2015.01.044

中图分类号：

R711.31 [阴道炎];

学科分类号：

摘要：

通过检索Pub Med、Cochrane Controlled Trial Register、OVID、万方、中国生物医学文献数据库和CNKI数据库,收集抗菌药物治疗细菌性阴道炎(BV)预防早产的临床随机对照试验的13篇文献,筛选、评价文献并提取数据进行Meta分析。抗菌药物治疗BV并不能降低早产发生率(OR=0.89,95%CI=[0.68,1.17],P=0.40);22孕周前使用抗菌药物治疗BV有助于降低早产发生率(OR=0.76,CI=[0.59,0.98],P=0.03)。在有充足的证据之前,不推荐使用抗菌药物治疗BV预防早产;22孕周前使用抗菌药物治疗BV有助于降低早产率,但该结论还有待研究来证实。

引用

页码：126 / 128

页数：3

共 9 条

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