肠缺血再灌流时肠内给予葡萄糖能增加肠黏膜血流量

被引：14

作者：

胡森

Rosemary A.Kozar

Frederick A.Moore

盛志勇

机构：

[1] 解放军第三四医院全军烧伤研究所,美国德克斯大学休斯敦医学院外科系,美国德克斯大学休斯敦医学院外科系,解放军第三四医院全军烧伤研究所

来源：

中华烧伤杂志 | 2001年 / 03期

关键词：

肠内营养; 黏膜血流; 缺血再灌流损伤;

D O I：

暂无

中图分类号：

R459.3 [饮食疗法、临床营养学];

学科分类号：

100215 ;

摘要：

目的　探讨肠缺血再灌流损伤时肠内营养与肠黏膜血流改变的关系。　方法　SD大鼠随机分为丙氨酸组 (12只 )、葡萄糖组 (14只 )和甘露醇对照组 (10只 )。先制作空肠袋 ,将激光多谱勒探头和肠黏膜张力计放置在空肠袋两端 ,分别向袋内注入丙氨酸、葡萄糖和甘露醇。用动脉夹阻断肠系膜上动脉血流 6 0min后 ,再恢复灌流 6 0min。每 30min分别测定肠黏膜血流量和局部PCO2 张力 (PrCO2 )。　结果　缺血再灌流过程中 ,与甘露醇组比较 ,葡萄糖组肠黏膜血流量显著增加 ,PrCO2降低 ,P <0 0 1。　结论　缺血再灌流过程中 ,肠内给予葡萄糖能增加肠黏膜血流量 ,对缺血再灌流损伤的肠道提供保护作用

引用

页码：10 / 12

页数：3

共 13 条

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