缝隙连接:一个潜在的肿瘤治疗新靶点附视频

被引：10

作者：

范高福

童旭辉

陶亮

机构：

[1] 蚌埠医学院药理学教研室

来源：

蚌埠医学院学报 | 2012年 / 02期

关键词：

肿瘤/治疗; 连接蛋白; 缝隙连接; 旁观者效应; 综述;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 [肿瘤学];

摘要：

<正>连接蛋白(connexin,Cxs)及其形成的缝隙连接细胞间通讯(gap junction cell-cell communication,GJIC)在肿瘤的生长、增殖、转移中起着重要的作用。研究[1]证实,在培养的正常细胞和肿瘤细胞,缝隙连接(gap junction,GJ)能够增强多种化学毒物引起细胞凋亡的作用。大量研究[2]表明,靶向Cxs

引用

页码：234 / 237

页数：4

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