儿童癫痫共患孤独症附视频

被引:15
作者
刘靖
李雪
机构
[1] 北京大学精神卫生研究所北京大学第六医院卫生部精神卫生学重点实验室国家精神心理疾病临床医学研究中心(北京大学)
关键词
癫痫; 孤独症; 共患病; 儿童;
D O I
暂无
中图分类号
R742.1 [癫痫]; R749.94 [儿童精神病];
学科分类号
100204 [神经病学];
摘要
癫痫和孤独症共患是较为常见的临床现象,5%37%的癫痫儿童共患孤独症(或孤独症筛查阳性),2%46%的孤独症或孤独症谱系障碍患者共患癫痫。精神疾病家族史、围生期不利因素、女性、孤独症特征、智力障碍、遗传或神经综合征、遗传因素等增加两种疾病共患风险。两种疾病共患时,癫痫起病更早,存在学龄前和青春期两个起病高峰,部分性发作更多见,难治性发生率更高,孤独症症状更严重,智力障碍更突出,运动发育问题和行为症状更多见,适应不良更明显。及时识别、正确诊断和规范治疗两种疾病非常重要。
引用
收藏
页码:252 / 256
页数:5
相关论文
共 19 条
[1]
Features of the broader autism phenotype in people with epilepsy support shared mechanisms between epilepsy and autism spectrum disorder[J] Annie E. Richard;Ingrid E. Scheffer;Sarah J. Wilson Neuroscience and Biobehavioral Reviews 2017,
[2]
Treatment Resistant Epilepsy in Autism Spectrum Disorder: Increased Risk for Females[J] Karen Blackmon;Judith Bluvstein;William S. MacAllister;Jennifer Avallone;Jade Misajon;Julie Hedlund;Rina Goldberg;Aviva Bojko;Nirmala Mitra;Radha Giridharan;Richard Sultan;Seth Keller;Orrin Devinsky Autism Research 2016,
[3]
Autism and behavior in adult patients with Dravet syndrome (DS)[J] J.J.L. Berkvens;I. Veugen;M.J.B.M. Veendrick-Meekes;F.M. Snoeijen-Schouwenaars;H.J. Schelhaas;M.H. Willemsen;I.Y. Tan;A.P. Aldenkamp Epilepsy & Behavior 2015,
[4]
Clinical characteristics of children and young adults with co-occurring autism spectrum disorder and epilepsy[J] Christelle M. El Achkar;Sarah J. Spence Epilepsy & Behavior 2015,
[5]
Epilepsy Among Children and Adolescents with Autism Spectrum Disorders: A Population-Based Study[J] Elina Jokiranta;Andre Sourander;Auli Suominen;Laura Timonen-Soivio;Alan S. Brown;Matti Sillanp?? Journal of Autism and Developmental Disorders 2014,
[6]
Routine developmental and autism screening in an epilepsy care setting[J] Breanne Fisher;Catherine Dezort;Douglas R. Nordli;Anne T. Berg Epilepsy and Behavior 2012,
[7]
Exploring the Relationship Between Autism Spectrum Disorder and Epilepsy Using Latent Class Cluster Analysis[J] Michael Cuccaro;Roberto Tuchman;Kara Hamilton;Harry Wright;Ruth Abramson;Jonathan Haines;John Gilbert;Margaret Pericak-Vance Journal of Autism and Developmental Disorders 2012,
[8]
Epilepsy and autism: Is there a special relationship?[J] Anne T. Berg;Sigita Plioplys Epilepsy and Behavior 2012,
[9]
A systematic review of two outcomes in autism spectrum disorder – epilepsy and mortality[J] SUEWOOLFENDEN;VANESSASARKOZY;GRETARIDLEY;MICHAELCOORY;KATRINAWILLIAMS Developmental Medicine & Child Neurology 2012,
[10]
Autism in Dravet syndrome: Prevalence; features; and relationship to the clinical characteristics of epilepsy and mental retardation[J] Bing-Mei Li;Xiao-Rong Liu;Yong-Hong Yi;Yu-Hong Deng;Tao Su;Xin Zou;Wei-Ping Liao Epilepsy and Behavior 2011,