MicroRNA在神经系统中的作用研究进展

被引：4

作者：

雷平

李耀华

杨树源

张建宁

机构：

[1] 天津医科大学总医院神经外科天津市神经病学研究所

来源：

中华神经医学杂志 | 2010年 / 02期

关键词：

microRNA; 神经系统; 发育; 基因调控;

D O I：

暂无

中图分类号：

Q42 [神经生理学];

学科分类号：

071003 [生理学];

摘要：

<正>一、MicroRNA概述MicroRNA(miRNA)是一类长度约为19～25个核苷酸的小分子RNA,通过与mRNA互补结合,在转录后水平抑制靶基因的表达。1993年Lee等首次在线虫中发现,基因Lin-4通过转录生成的RNA调控虫体的发育过程。2000年

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