接种流感病毒疫苗后触发系统性红斑狼疮一例并文献复习

被引:4
作者
杨程德
鲍春德
张巍
俞翀曌
陈顺乐
顾越英
机构
[1] 上海第二医科大学附属仁济医院风湿科
关键词
红斑狼疮,系统性; 病理学,临床; 流感疫苗;
D O I
暂无
中图分类号
R593.241 [];
学科分类号
1002 ; 100201 ;
摘要
目的 探讨外界环境因素在系统性红斑狼疮 (SLE)发病机制中的作用。方法 报道1例男性 14岁患者在接种流感病毒疫苗后触发了SLE疾病的发生 ,并对患者的一级亲属的血清进行了免疫学检测。结果 患儿父亲血清中有高滴度的抗核抗体。结论 外界环境因素如流感病毒疫苗免疫注射可能触发有内在遗传基因背景的个体发生SLE。对有SLE易感倾向的个体及SLE患者应减少非计划内免疫接种的次数
引用
收藏
页码:46 / 48
页数:3
相关论文
共 11 条
[1]  
Influenza virus vaccination of patients with systemic lupus erythematosus effects on disease activity. Abu-Shakra M,Zalmanson S,Neumann L,et al. The Journal of Rheumatology . 2000
[2]  
Disseminated lupus erythematosus: an allergic disease. Fox RA. Archives of Pathology . 1943
[3]  
Polyarteritis after influenza vaccination. Wharton CFP,Pietroni R. British Medical Journal . 1974
[4]  
Systemic lupus erythematosus. Mill JA. The New England Journal of Medicine . 1994
[5]  
Neurological complications of immunization. Fenichel GM. Annals of Neurology . 1982
[6]  
Systemic lupus erythematosus following hepatitis B vaccine. Guiserix J. Nephron . 1996
[7]  
Can immunization precipitate connective tissue disease?Report of five cases of systemic lupus erythematosus and review of the literature. Older SA,Battafarano DF,Enzenauer RJ,et al. Seminars in Arthritis and Rheumatism . 1999
[8]  
Disseminated lupus erythematosus occurring among student nurses. Ayvazin LF,Badger TL. The New England Journal of Medicine . 1948
[9]  
Systemic lupus erythematosus and vaccination against hepatitis B. Tudela P,Marti S,Bonal J,et al. Nephron . 1992
[10]  
Rheumatic disorders developed after hepatitis B vaccination. Maillefert JF,Sibilia J,Toussirot B,et al. Rheumatology . 1999