基质金属蛋白酶2及其基因多态性与动脉粥样硬化的关系

被引：2

作者：

王凤

金笑平

机构：

[1] 台州医院神经内科

来源：

医学综述 | 2010年 / 20期

基金：

浙江省自然科学基金;

关键词：

基质金属蛋白酶2; 基因多态性; 动脉粥样硬化;

D O I：

暂无

中图分类号：

R543 [血管疾病];

学科分类号：

1002 ; 100201 ;

摘要：

基质金属蛋白酶2(MMP-2)是基质金属蛋白酶类的重要成员,是MMPs相互作用的关键酶。MMP-2参与动脉粥样硬化的发生、发展,其水平受多种因素的影响。MMP-2的基因多态性与血浆MMP-2的水平相关,共同参与动脉粥样硬化相关各种疾病的发生、发展。现从MMP-2和其基因多态性与动脉粥样硬化相关的疾病关系进行综述。

引用

页码：3041 / 3043

页数：3

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