雌激素及选择性雌激素受体调节剂对骨关节炎作用的研究进展

被引：18

作者：

陈天钢 ^{[1
]}

勾禹 ^{[2
]}

田发明 ^{[3
]}

张柳 ^{[4
]}

机构：

[1] 华北理工大学研究生学院

[2] 河北医科大学研究生院

[3] 华北理工大学医学实验研究中心

[4] 华北理工大学附属医院骨科

来源：

中国临床药理学杂志 | 2018年 / 34卷 / 01期

关键词：

骨关节炎; 雌激素; 选择性雌激素受体调节剂; 软骨下骨; 软骨; 滑膜;

D O I：

10.13699/j.cnki.1001-6821.2018.01.020

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

目前骨关节炎的发病机制仍未明确,绝经期女性骨关节炎发病率明显升高,这可能与绝经期女性的雌激素减少有关。本文通过研究软骨下骨、软骨和滑膜的病变机制,综述雌激素及选择性雌激素受体调节剂对骨关节炎的影响。

引用

页码：73 / 76

页数：4

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