缺血性卒中后非流利型失语患者静息态功能磁共振比率低波振幅的研究

被引:8
作者
许光 [1 ,2 ]
马晓芬 [1 ]
江桂华 [1 ]
李淑美 [1 ]
田军章 [1 ]
詹文峰 [1 ]
方金 [1 ]
邱迎伟 [1 ]
机构
[1] 南方医科大学附属广东省第二人民医院
[2] 南方医科大学第三临床医学院
基金
广东省自然科学基金;
关键词
卒中; 缺血性卒中后非流利型失语; 功能磁共振成像; 比率低频振幅;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
100204 [神经病学];
摘要
目的:对缺血性卒中后非流利型失语症患者的静息态功能磁共振原始数据进行比率低频振幅的处理分析,探讨其脑功能损伤及代偿的病理机制。方法:对17例失语患者(患者组)及19例年龄、性别、受教育程度均匹配的健康对照者(正常组)进行静息状态下的功能磁共振成像扫描,扫描序列为回波平面成像序列,应用DPARSF软件进行数据处理,并进行对比分析。结果:同正常组比较,患者组右侧颞上回、顶下小叶、中央后回及额叶皮层的fALFF值增高;右侧丘脑及双侧的小脑半球的fALFF值明显降低。结论:静息状态下,缺血性卒中后非流利型失语的患者在某些脑区存在异常激活,反映其脑功能失调的病理变化,为临床从大脑神经活动层面进一步了解失语症损伤及其代偿过程提供了客观依据。
引用
收藏
页码:1016 / 1020
页数:5
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