M受体亚型和胃肠道平滑肌功能

被引:36
作者
王斌
程峰涛
机构
[1] 上海市杨浦区中心医院消化科,上海市杨浦区中心医院消化科上海,上海
关键词
毒蕈碱; 肌,平滑; 胃肠系统;
D O I
暂无
中图分类号
R33 [人体生理学];
学科分类号
100123 [人体微生态学];
摘要
The muscarinic receptor family expressed in smooth muscle throughout the body is thought to be composed of five subtypes coupling to distinct signaling systems,respectively.The population in smooth muscle is composed of mainly M 2 and M 3 subtypes in a 80% to 20% mixture. The muscarinic receptor, mainly M 3 receptor, play an important role in regulating gastrointestinal smooth muscle contraction. Selective muscarinic M 3 antagonist should have therapeutic utility in the treatment of gastrointestinal disease.
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页数:4
相关论文
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常用药物手册.[M].张家铨等编;.人民卫生出版社.1987,