“脑还丹”对老龄去势大鼠血清IGF-Ⅰ和血脂水平的影响

被引:8
作者
程志安
李庆明
曾志勇
谢文峰
李红毅
机构
[1] 中山大学孙逸仙纪念医院
[2] 广州中医药大学附二院
[3] 广州中医药大学附二院 广州
关键词
胰岛素样生长因子; 血脂; 脑还丹;
D O I
10.13422/j.cnki.syfjx.2002.01.015
中图分类号
R285.5 [中药实验药理];
学科分类号
1008 ;
摘要
为了探讨“脑还丹”防治神经原退行性变的机制 ,本文从血清IGF Ⅰ和血脂的变化观察了该方对老龄去势大鼠 (肾虚模型 )的病理生理影响。结果表明 ,“脑还丹”能显著降低卵巢结扎大鼠LDL c和TC的血清浓度 ,高剂量可显著提高HDL、TG和血清IGF Ⅰ的水平。说明“脑还丹”保护神经原的作用是通过调节血脂及IGF Ⅰ水平等途径实现的。
引用
收藏
页码:38 / 40
页数:3
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