一氧化氮在突出腰椎间盘中的表达

被引:2
作者
郭乐斌
曹盛俊
机构
[1] 南华大学第一附属医院
[2] 南华大学第一附属医院 湖南衡阳
[3] 湖南衡阳
关键词
一氧化氮; 一氧化氮合酶; 腰椎间盘突出症; 坐骨神经痛;
D O I
暂无
中图分类号
R681.53 [];
学科分类号
1002 ; 100210 ;
摘要
目的 探讨一氧化氮 (NO)在腰椎间盘退变及腰椎间盘突出症引起的坐骨神经痛发生中可能起到的作用。方法 测定 2 5例腰椎间盘突出症患者手术取出的髓核组织中一氧化氮、一氧化氮合酶 (NOS)的含量。以 5例新鲜尸体的腰椎间盘髓核组织作为正常对照。对患者坐骨神经痛的程度以Dallas疼痛调查表作评分。结果 在腰椎间盘髓核组织中测得NO与NOS的存在 ,患者组含量明显高于正常对照组 (P <0 .0 1 )。NO的含量与疼痛程度有相关性。结论 在腰椎间盘退变及腰椎间盘突出症引起的坐骨神经痛的发生中 ,一氧化氮可能起到某种重要作用。
引用
收藏
页码:123 / 125
页数:3
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