Wistar鼠胃肠道的粘液分布

被引:2
作者
李春启
刘为纹
王振华
姜利国
机构
[1] 第三军医大学西南医院消化科
关键词
大鼠; 近交系; 肠粘膜; 粘液; 组织化学;
D O I
10.16016/j.1000-5404.1992.06.008
中图分类号
学科分类号
摘要
本文应用粘液组化技术对Wistar鼠胃肠道的粘液分布进行观察,并与人类胃肠道的粘液分布作了比较。结果表明人与鼠胃和结肠中的粘液分布具有相似性,胃粘膜主要含中性粘液,小凹底部和腺颈部含少量唾液酸粘液。从近端结肠向远端结肠,中性与唾液粘液逐渐减少,而硫酸粘液逐渐增多,左右半结肠粘膜中粘液分布特点亦明显不同。在小肠,硫酸粘液只见于人回肠末端,而Wistar鼠空肠与回肠中均含硫酸粘液。这些结果为在人体及动物实验中,判断胃肠道某些病理情况下粘液质和量的异常提供了依据。
引用
收藏
页码:528 / 530
页数:3
相关论文
共 8 条
[1]  
Diamine methods for differentiating mucosubstances histochmically. Spicer SS. Journal of Histochemistry and Cytochemistry . 1965
[2]  
Autoradiographic studies on the mucin metabolism in human gastric mucosa with special reference to intestinal metaplasia. Shimamoto K,Kawai K,Murakami K,et al. Acta Hepato-Gastroenterol . 1973
[3]  
Epithelial ABH iscantigen loss in adenomatous polyps and carcinoma of the colon. Sheahan DG. Gastroenterology . 1975
[4]  
Sulphoglycoprotein antigens in the human alimentary canal and gastric cancer, a immunohistological study. Hakkinen I,Jarvi O,Gronroos J. International Journal of Cancer . 1968
[5]  
Studies on gastric mucins in health and disease. Hoskins LC,Zamcheck N. Annals of the New York Academy of Sciences . 1963
[6]  
A study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis in precancerous lesions of stomach. Li Chunqi,Liu Weiwen. Journal of Gastroenterology and Hepatology . 1991
[7]  
Mucous secretion in rat colonic mucosa during carcinogenesis induced dimethylhydrazine, a morphological and histochemical study. Filipe MI. British Journal of Cancer . 1975
[8]  
Measurement of sulphated and non-sulphated glycoproteins in human gastric juice under fasting conditions and following stimulation with histamine, pentagastrin and insulin. Glass GBJ,Mori H,Pamer T. Digestion . 1969