HIGH EFFICIENCY RETROVIRUS-MEDIATED GENE TRANSFERTO LEUKEMIA CELLS

被引:4
作者
傅建新
陈子兴
岑建农
王玮
阮长耿
机构
关键词
Retrovirus; Leukemia; Gene transfer; Transefection; Gene therapy; Polymerase chain reatction;
D O I
暂无
中图分类号
R733.7 [白血病];
学科分类号
100214 ;
摘要
Genetherapywithgenetransferasitsmolecularbasispromisesaneffectivestrategyforthetreatmentofcancerandinheriteddiseases.RetroviralvectorsderivedfromtheMoloneymurineleukemiavirus(MoMLV)backbonearewidelystudiedasvehiclesforgenetransferbasedontheirpotentia...
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页码:3 / 5
页数:5
相关论文
共 7 条
[1]  
Bagnis C,Chabannon C.Mannoni P Gene transferinto haemopoietic cells f a challenge for gene therapy. Gene Therapy . 1996
[2]  
Lynch CM,Miller AD.Production of high-titer helpervirus-free retroviral vectors by cocultivation ofpackaging cells with different host ranges. Journal of Virology . 1991
[3]  
Tafuro S,Zentilin L,Falaschi A,et al.Rapidretrovirus titration using competitive polymerasechain reaction. Gene Therapy . 1996
[4]  
Smith KT,Shepherd AJ,Boyd JE,et al.Gene deliverysystems for use in gene therapy’ an overview ofquality assurance and safety issues. Gene Therapy . 1996
[5]  
Wu T,Bloom ML,Yu J-M,et al.Murine bone marrowexpressing the neomycin resistance gene has nocompetitive disadvantage assessed in vivo. Human Gene Therapy . 1998
[6]  
Limon A,Briones J,Puig T,et al.High-titer vectorscontaining the enhanced green fluorescent proteingene for efficient expression in hematopoietic cells. Blood . 1997
[7]  
Pages J-C,Loux N,Farge D,et al.Activation ofMoloney murine leukemia virus LTR enhances thetiter of recombinant retrovirus in W CRIP packagingcells. Gene Therapy . 1995