自噬在维持肠道内稳态中的作用

被引：7

作者：

吴振婷

秦少游

贾二娜

葛安琪

周长玉

机构：

[1] 吉林大学中日联谊医院消化内科

来源：

国际消化病杂志 | 2016年 / 36卷 / 05期

关键词：

自噬; 肠道内稳态; 细胞生物学;

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

肠道内稳态依赖于肠道菌群、肠上皮细胞及肠黏膜免疫细胞间复杂的相互作用,不同类型肠细胞通过多种途径调节肠道微生态、限制致病菌、调控肠道局部炎性反应。自噬参与组织细胞的免疫应答及免疫防御。目前有文献报道,自噬对维持肠道内稳态也起着重要的作用。学者们通过建立自噬缺陷细胞模型发现,自噬异常可影响不同类型肠细胞的功能,进而导致肠道内稳态失衡和慢性肠道炎性疾病发生,该文就此作一综述。

引用

收藏

页码：273 / 276

页数：4

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