黄芪成分F3增强低剂量白介素Ⅱ诱导LAK细胞的细胞毒效应

被引：17

作者：

储大同

孙燕

林娟如

WongWendy

MavligitG

机构：

[1] 中国医学科学院肿瘤研究所,中国医学科学院肿瘤研究所,中国医学科学院肿瘤研究所,美国德克萨斯州大学MDAnderson肿瘤中心,美国德克萨斯州大学MDAnderson肿瘤中心肿瘤医院(),肿瘤医院(),肿瘤医院()

来源：

中西医结合杂志 | 1990年 / 01期

关键词：

黄芪; 白介素Ⅱ; LAK 细胞;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

在对黄芪免疫调节有效成分 F3的研究过程中发现:(1)F3加入100u/ml 白介素Ⅱ(rIL-2),其所诱导的 LAK 细胞对人类黑色素瘤 A375P 的杀伤率可达80%,与1000u/ml rIL-2单独使用时的效果(76%)相似,减少 rIL-2用量的90%。(2)使用 F3后,所需 LAK细胞数量减少50%。提示运用其他生物反应调节剂(BRMs)来增强 rIL-2所诱导的 LAK 细胞杀伤活性是一个值得探索的方向。

引用

页码：34 / 36+5 +5

页数：4

共 14 条

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