PCBs对斑马鱼鳃及肝脏细胞超微结构的影响的初步研究

Zebrafish (Brachydanio rerio) were exposed to PCBs (50 μg/L) for 4 weeks. The gill and the liver morphology were examined by transmission eletron microslogy. Results indicated that the membrane and partial cytoplasm of the epithelium cell in secondary lamella collapsed with lots of mucous and cell debris lying around. Hepatic cells which exposed to PCBs for 4 weeks showed the deforming nuclear deviated from cell centre, mitochondrim collapsed and rough-surfaced endoplasmic reticulum fractured. Furthermore, there were lots of lipofuscin granule and lipid droplet in the cytoplasm of the damaged cells.