阿托伐他汀治疗冠心病合并脑梗死的临床研究

被引:16
作者
徐南飞
陈晓雷
马志伟
冯涛
机构
[1] 南京医科大学附属无锡市第二人民医院神经内科
基金
教育部留学回国人员科研启动基金;
关键词
阿托伐他汀; 苯磺酸氨氯地平; 冠心病; 脑梗死;
D O I
10.13241/j.cnki.pmb.2014.35.030
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)]; R743 [脑血管疾病];
学科分类号
100201 [内科学]; 100204 [神经病学];
摘要
目的:研究阿托伐他汀联合苯磺酸氨氯地平治疗冠心病合并脑梗死的临床效果。方法:从2011年1月到2013年1月,在我院共有96例病患被诊断为冠心病合并脑梗死。以数字法随机分成观察组(48例)和对照组(48例)。对照组每天口服苯磺酸氨氯地平,观察组在对照组的基础上口服阿托伐他汀钙片。对比两组疗效及病患血脂水平。结果:观察组疗效为优者占比62.50%(30/48),优良率为91.67%(44/48),均显著高于对照组的39.58%(19/48),75.00%(36/48),差异均有统计学意义(均P<0.05);观察组治疗后TC(4.74±1.20)mmol/L,显著性低于对照组(5.22±1.15)mmol/L,TG(1.06±0.30)mmol/L,显著性低于对照组(1.51±0.28)mmol/L,LDL-C(3.19±0.51)mmol/L,显著性低于对照组(3.87±0.25)mmol/L,上述差异均有统计学意义(P<0.05)。结论:阿托伐他汀联合苯磺酸氨氯地平治疗冠心病合并脑梗死,不仅可明显提升治疗效果,还可减少病患的并发症的发生。方便安全,值得临床推荐。
引用
收藏
页码:6913 / 6915
页数:3
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