双膦酸盐相关性颌骨坏死

被引：24

作者：

潘剑

王杞章

刘济远

机构：

[1] 口腔疾病研究国家重点实验室华西口腔医院口腔颌面外科(四川大学)

来源：

华西口腔医学杂志 | 2017年 / 01期

关键词：

双膦酸盐; 颌骨; 骨坏死;

D O I：

暂无

中图分类号：

R782 [口腔颌面部外科学];

学科分类号：

100302 [口腔临床医学];

摘要：

双膦酸盐类(BPs)药物是一种强有力的骨吸收抑制剂,已广泛应用于临床治疗中。近年来,有关双膦酸盐相关性骨坏死(BRONJ)的报道日渐增多,该病临床上以骨面裸露、死骨形成、疼痛、口臭等为特征。由于目前发病机理不明确,临床上尚无完全有效的治疗方法,因此BRONJ的预防十分重要。本文就BRONJ的发病机制、危险因素、临床特征、治疗预后等方面的研究现状进行阐述,以期为临床提供帮助。

引用

页码：29 / 36

页数：8

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