IL-6、CRP、CA125在卵巢肿瘤定性诊断中的价值及临床意义

被引：4

作者：

马丽丽

刘萍

满淑红

机构：

[1] 山东省潍坊市人民医院妇产科!潍坊

来源：

现代妇产科进展 | 2001年 / 05期

关键词：

卵巢肿瘤; 白细胞介素6; 抗原,肿瘤相关,碳水化合物; 诊断应用;

D O I：

10.13283/j.cnki.xdfckjz.2001.05.015

中图分类号：

R737.31 [卵巢肿瘤];

学科分类号：

100214 ;

摘要：

目的 :探讨测定血清IL 6、CRP、CA12 5水平在卵巢肿瘤定性诊断中的价值及临床意义。方法 :取卵巢肿瘤 61例患者的血浆及 17例合并腹水患者的腹水 ,用ELISA法及胶乳凝集法测定IL 6、CA12 5、CRP。结果 :IL 6诊断卵巢癌敏感性为 80 .9% ,特异性为77.3%。CA12 5诊断卵巢癌敏感性为 85 .7% ,特异性为 80 .9%。这二项指标联合检测 ,敏感性为 92 .5 % ,特异性 73.9%。CRP诊断卵巢癌敏感性达 76.2 % ,特异性 60 .0 %。临床分期晚、组织分化低者血清及腹水IL 6、CA12 5水平明显升高。结论 :IL 6、CA12 5是卵巢肿瘤定性诊断的良好指标 ,联合检测可提高定性诊断的敏感性及特异性。腹水或血中IL 6、CA12 5水平可为卵巢癌早期诊断、分期及判断预后提供有效的参考指标。

引用

页码：364 / 366

页数：3

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