肿瘤微环境内免疫耐受机制研究进展

[1] Mechanisms of tumor escape: role of tumor microenvironment in inducing apoptosis of cytolytic effector cells[J] . Alessandro Poggi,Maria Raffaella Zocchi. &nbspArchivum Immunologiae et Therapiae Experimentalis . 2006 (5)

[2] Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Peng G,Guo Z,Kiniwa Y, et al. Science . 2005

[3] Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Cureil TJ,Coukos G,Zou L,et al. Nature Medicine . 2004

[4] Foxp3 expressingCD4+CD25(high)regulatory T cells are overrepresented inhuman metastatic melanoma lymph nodes and inhibit thefunction of infiltrating T cells. Viguier M,Lemaitre F,Verola O,et al. J Immunol . 2004

[5] Concomitant tumor immunity to a poorly im-munogenic melanoma is prevented by regulatory Tcells. Turk M J,GUEVARA-PATINO J A,RIZZUTO GA,et al. The Journal of Experimental Medicine . 2004

[6] Restored immune response to an MHC-II-Restricted antigen in tumor-bearing hosts after elimination of regulatory T cells. Michael Nicholl Andrew Lodge Ian Brown and Sonia L. Sugg. Journal of Pediatric Nursing . 2004

[7] Intratumoral CD4+CD25+regulatory T-cell-mediated suppression of infil-trating CD4+T cells in B-cell non-Hodgkin lymphoma. Yang ZZ,Novak AJ,Stenson MJ,et al. Blood . 2006

[8] Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells. Steinbrink K,Jonuleit H,Muller G,et al. Blood . 1999

[9] Regulation of Tcell re-ceptor CD3zeta chain expression by L-arginine. Rodriguez PC,Zea AH,Culotta KS,et al. Journal of Biological Chemistry . 2002

[10] Arginase I produc-tion in the tumor microenvironment by mature myeloid cells inhib-its T-cell receptor expression and antigen-specific T-cell re-sponses. Rodriguez PC,Quiceno DG,Zabaleta J,et al. Cancer Research . 2004

[1] Mechanisms of tumor escape: role of tumor microenvironment in inducing apoptosis of cytolytic effector cells[J] . Alessandro Poggi,Maria Raffaella Zocchi. &nbspArchivum Immunologiae et Therapiae Experimentalis . 2006 (5)

[2] Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Peng G,Guo Z,Kiniwa Y, et al. Science . 2005

[3] Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Cureil TJ,Coukos G,Zou L,et al. Nature Medicine . 2004

[4] Foxp3 expressingCD4+CD25(high)regulatory T cells are overrepresented inhuman metastatic melanoma lymph nodes and inhibit thefunction of infiltrating T cells. Viguier M,Lemaitre F,Verola O,et al. J Immunol . 2004

[5] Concomitant tumor immunity to a poorly im-munogenic melanoma is prevented by regulatory Tcells. Turk M J,GUEVARA-PATINO J A,RIZZUTO GA,et al. The Journal of Experimental Medicine . 2004

[6] Restored immune response to an MHC-II-Restricted antigen in tumor-bearing hosts after elimination of regulatory T cells. Michael Nicholl Andrew Lodge Ian Brown and Sonia L. Sugg. Journal of Pediatric Nursing . 2004

[7] Intratumoral CD4+CD25+regulatory T-cell-mediated suppression of infil-trating CD4+T cells in B-cell non-Hodgkin lymphoma. Yang ZZ,Novak AJ,Stenson MJ,et al. Blood . 2006

[8] Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells. Steinbrink K,Jonuleit H,Muller G,et al. Blood . 1999

[9] Regulation of Tcell re-ceptor CD3zeta chain expression by L-arginine. Rodriguez PC,Zea AH,Culotta KS,et al. Journal of Biological Chemistry . 2002

[10] Arginase I produc-tion in the tumor microenvironment by mature myeloid cells inhib-its T-cell receptor expression and antigen-specific T-cell re-sponses. Rodriguez PC,Quiceno DG,Zabaleta J,et al. Cancer Research . 2004