脑源性神经营养因子与抑郁症

被引：10

作者：

张璐璐

郑洪波

马崔

机构：

[1] 广州医学院附属脑科医院(广州脑科医院)

来源：

国际精神病学杂志 | 2009年 / 36卷 / 01期

关键词：

脑源性神经营养因子; 抑郁症; 基因多态性; 抗抑郁药;

D O I：

10.13479/j.cnki.jip.2009.01.013

中图分类号：

R749.4 [情感性精神病];

学科分类号：

100205 ;

摘要：

神经营养因子是神经元网络形成和可塑性的重要调节因子,以脑源性神经营养因子(BDNF)最受关注。抗抑郁治疗通过提高BDNF表达来促进神经元可塑性,从而取得疗效。本文从临床前研究、临床研究和基因多态性等方面对BDNF与抑郁症作一综述。

引用

页码：30 / 32

页数：3

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