肥胖与青少年多囊卵巢综合征

被引：28

作者：

孙晶 ^{[1
]}

王勇 ^{[1
]}

吴效科 ^{[2
]}

机构：

[1] 南京大学医学院江苏省医学分子技术重点实验室

[2] 黑龙江中医药大学附属第一医院妇产科

来源：

国际妇产科学杂志 | 2009年 / 36卷 / 05期

关键词：

多囊卵巢综合征; 青少年; 肥胖; 胰岛素抵抗; 代谢综合征;

D O I：

暂无

中图分类号：

R711.75 [卵巢疾病];

学科分类号：

100211 [妇产科学];

摘要：

多囊卵巢综合征(PCOS)是育龄妇女常见生殖内分泌疾病。近年发现,随着儿童肥胖患病率增加,青少年PCOS发病率也逐年提高。肥胖可通过增加外周循环胰岛素水平影响PCOS发病机制,PCOS患者高雄激素血症也会增加内脏脂肪沉积。肥胖会增加与PCOS相关的代谢和心血管方面的并发症的患病风险,如胰岛素抵抗(IR)、高脂血症、高血压以及临床症状不明显的动脉粥样硬化等。早期识别青春期PCOS,有利于及时纠正、阻断其内分泌紊乱,防止近期及远期并发症发生。

引用

页码：343 / 347

页数：5

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