临床Ⅰ期非小细胞肺癌淋巴结转移的影响因素及临床意义

被引:5
作者
张真发
李军
尚文军
张林
机构
[1] 中国医科大学第一附属医院胸外科
[2] 中国医科大学第一附属医院胸外科 沈阳
[3] 沈阳
关键词
临床Ⅰ期; 病理分期; 非小细胞肺癌; 淋巴结转移;
D O I
暂无
中图分类号
R734.2 [肺肿瘤];
学科分类号
100214 ;
摘要
目的 分析临床Ⅰ期非小细胞肺癌患者肺内和纵隔淋巴结转移的影响因素 ,从而进一步探讨临床Ⅰ期非小细胞肺癌的治疗方式。方法 选择从 1999年 7月到 2 0 0 1年 4月行肺叶切除及纵隔或肺内淋巴结廓清手术的临床Ⅰ期非小细胞肺癌患者共 15 9名 ,进行回顾性分析 ,应用logistic单因素和多因素分析来判断影响淋巴结转移的因素。结果 全组 15 9例临床Ⅰ期非小细胞肺癌患者中 ,3 7例 ( 2 3 % )患者有淋巴结转移。依据logistic回归分析 ,肿瘤直径、分化程度及胸膜侵袭是淋巴结转移的影响因素 (P =0 .0 0 3 ,P =0 .0 0 4,P =0 .0 0 5 )。有 2个或 2个以上因素与小于 2个因素比较 ,局部淋巴结转移的可能性明显增大 (P <0 .0 0 1)。结论 临床Ⅰ期非小细胞肺癌患者表现为肿瘤直径 >2cm、肿瘤分化中 /差或侵及胸膜时 ,淋巴结转移可能性较大。这种情况下对治疗方式的选择及预后的判断应慎重
引用
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页码:298 / 300
页数:3
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