转化生长因子—β族信号转导与肿瘤

被引:3
作者
张平
机构
[1] 浙江中医学院病理学教研室!浙江杭州
关键词
转化生长因子β; 信号传递; 肿瘤;
D O I
暂无
中图分类号
R730.2 [肿瘤病理学、病因学];
学科分类号
100214 ;
摘要
Cytokines of the transforming growth factor (TGF-β)family exert multiple biological effects by their signal transduction pathways that undergo a basic course of ligands of TGF-β family→receptors→SMADs→transcription factors→DNA expression. The genetic variety of different signal molecules in transduction pathways of TGF-β family were found in various benign or malignant tumors, and this had much significance in designing effective therapeutic strategy.
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页码:90 / 93
页数:4
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