他汀类药物与痴呆

[1] The antithrombotic effect of statins. Kearney D,Fizgerald D. Journal of the American College of Cardiology . 1999

[2] Simvastatin strongly re-duces levels of Alzheimer’s diseaseβ-amyloid peptides Aβ42and Aβ40in vitro and in vivo. Fassbender K,Sinons M,Bergmann C,et al. Proceedings of the National Academy of Sciences of the United States of America . 2001

[3] Long-termeffects of pravas-tatin on plasma concentration of C-reactive protein.The Cholesterol and Recurrent Events(CARE)Investigators. Ridker PM,Rifain N,Pfeffer MA,et al. Circulation . 1999

[4] Relation of plasma lipids to Alzheimer disease and vascular dementia. Reitz C,Tang MX,Luchsinger J,et al. Archives of Neurology . 2004

[5] Neurology[C]. The 5th International Congress of Pathophysiology,2006

[6] MRC/BHF Heart Protec-tion Study of cholesterol lowering with simvastatin in20,536high-risk individuals:a randomised placebo-controlled trial. Heart Protection Study Collaborative Group. The Lancet . 2002

[7] Amyloidβ-protein interactions with membranes and cholesterol:causes or casualties of Alzheimers’disease. Gibson Wood W,Eckert GP,Igbavboa U,et al. Biochimica et Biophysica Acta . 2003

[8] Brain cholesterol:long secret life behind a barrier. Bjorkhem I,Meaney S. Arteriosclerosis and Thrombosis . 2004

[9] Quantifying effect of statins on low density lipoprotein cholesterol,ischaemic heart disease,and stroke:systematic reviewand meta-analysis. LawMR,Wald NJ,Rudnicka AR,et al. British Medical Journal . 2003

[10] Neurology[C]. The 5th International Congress of Pathophysiology,2006

[1] The antithrombotic effect of statins. Kearney D,Fizgerald D. Journal of the American College of Cardiology . 1999

[2] Simvastatin strongly re-duces levels of Alzheimer’s diseaseβ-amyloid peptides Aβ42and Aβ40in vitro and in vivo. Fassbender K,Sinons M,Bergmann C,et al. Proceedings of the National Academy of Sciences of the United States of America . 2001

[3] Long-termeffects of pravas-tatin on plasma concentration of C-reactive protein.The Cholesterol and Recurrent Events(CARE)Investigators. Ridker PM,Rifain N,Pfeffer MA,et al. Circulation . 1999

[4] Relation of plasma lipids to Alzheimer disease and vascular dementia. Reitz C,Tang MX,Luchsinger J,et al. Archives of Neurology . 2004

[5] Neurology[C]. The 5th International Congress of Pathophysiology,2006

[6] MRC/BHF Heart Protec-tion Study of cholesterol lowering with simvastatin in20,536high-risk individuals:a randomised placebo-controlled trial. Heart Protection Study Collaborative Group. The Lancet . 2002

[7] Amyloidβ-protein interactions with membranes and cholesterol:causes or casualties of Alzheimers’disease. Gibson Wood W,Eckert GP,Igbavboa U,et al. Biochimica et Biophysica Acta . 2003

[8] Brain cholesterol:long secret life behind a barrier. Bjorkhem I,Meaney S. Arteriosclerosis and Thrombosis . 2004

[9] Quantifying effect of statins on low density lipoprotein cholesterol,ischaemic heart disease,and stroke:systematic reviewand meta-analysis. LawMR,Wald NJ,Rudnicka AR,et al. British Medical Journal . 2003

[10] Neurology[C]. The 5th International Congress of Pathophysiology,2006