兔膝关节制动引起关节软骨退变的实验研究

被引：43

作者：

邱贵兴

王桂生

机构：

[1] 中国医学科学院北京协和医院骨科

来源：

中华外科杂志 | 1987年 / 03期

关键词：

D O I：

暂无

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

本文报告了用52只家兔进行膝关节制动与退变关系的研究结果。通过关节活动度、X线、肉眼、光镜、（35）S放射自显影和扫描电镜等观察,发现固定于功能位者8～12周时出现轻度改变,固定于伸直位者4周即有改变。随着固定时间的延长,病变逐渐加重。实验结果还提示软骨细胞有一定修复能力,但极为有限。软骨表面细胞受损,关节囊纤维化后,病变即为不可逆性改变。骨赘是晚期退变的表现。

引用

页码：175 / 177 +190-191+199

共 18 条

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