药物血浆蛋白结合率测定方法的研究进展

被引：130

作者：

刘睿

谢跃生

潘桂湘

刘志东

张伯礼

机构：

[1] 天津中医药大学中医药研究院,教育部省部共建方剂学重点实验室

来源：

天津中医药 | 2007年 / 06期

关键词：

血浆蛋白结合率; 平衡透析法; 超滤法; 微透析法; 高效亲和色谱法; 高效前沿分析法;

D O I：

暂无

中图分类号：

R96 [药理学];

学科分类号：

100706 [药理学];

摘要：

<正>药物血浆蛋白结合率是药物与血浆蛋白结合的量占药物总浓度的百分率,是药物代谢动力学的重要参数之一。它影响药物在体内的分布、代谢与排泄,从而影响其作用强度和时间,并往往与药物的相互作用及作用机制等密切相关。因此,

引用

页码：526 / 528

页数：3

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