β受体阻滞剂在慢性心力衰竭的应用

被引:24
作者
孙忠实
朱珠
机构
[1] 北京海军总医院,中国医学科学院!北京,中国协和医科大学北京协和医院药剂科
关键词
β受体阻滞剂; 心力衰竭;
D O I
暂无
中图分类号
R541.6 [血液循环衰竭];
学科分类号
1002 ; 100201 ;
摘要
目的:介绍本世纪末心血管药物治疗的最重要进展———β受体阻滞剂在慢性心力衰竭的应用,供临床医师、药师在转变治疗该病观念时参考。方法:收集近年来国外发表的有关资料加以归纳、综述,从药物治疗慢性心力衰竭的历史发展,至当代治疗的新观念作一概述。结果:依据循证医学原则,引用多个临床观察报告,肯定了β受体阻滞剂在治疗慢性心力衰竭中的重要地位,也反证了心力衰竭征候群是神经激素与血流动力学因素相互作用形成的新观念。结论:β受体阻滞剂适用于扩张型或缺血型、心功能Ⅱ~Ⅳ级的慢性心力衰竭。该病再也不是β受体阻滞剂的禁忌证。
引用
收藏
页码:3 / 6
页数:4
相关论文
共 20 条
[1]  
Clinicaleffectsofβ Adren ergicblockadeinthechronicheartfailure Ameta analysisofdouble blind ,placebo controlled ,randomizedtrials. LechatP .PackerM,ChalonS,etal. Circulation . 1998
[2]  
Design of the Cardiac insufficiency bisoprolol study Ⅱ (CIBIS Ⅱ). The CIBIS Scientific Committees. The Lancet . 1999
[3]  
Roleofadrenergicre ceptordownregulationinthepeakexerciseresponseinpatientswithheartfailureduetoidiopathicdilatedcardiomyopathy. WhiteM,YannowitzF,GilbertEM,etal. The American Journal of Cardiology . 1995
[4]  
The effect of digoxin on mortality and morbidity in patients with heart failure. The Digitalis Investigation Group. The New England Journal of Medicine . 1997
[5]  
Effect of chronic beta- adrenergic receptor blockade in congestive cardiomyopathy. Waagstein F,Hjalmarson A,Varnauskas E,et al. British Heart Journal . 1975
[6]  
Treatment guidelines in heart failure. Konstam MA,Remme WJ. Progress in Cardiovascular Diseases . 1998
[7]  
cardiologist’s perspective on evolving concepts in the management of congestive heart failure. Forker AD. Journal of Clinical Pharmacology . 1996
[8]  
Current guidelines for the treatment of congestive heart failure. Kleber FX,Wensel R. Drugs . 1996
[9]  
Rational, design, and organization of the metoprolol CR/XL randomized intervention trial in heart failure (MERIT-HF). THE INTERNATIONAL STEERING COMMITTEE ON BEHALF OF THEMERITHF STUDY GROUP. The American Journal of Cardiology . 1997
[10]  
Prolongationofsurvivalincongestivecardiomyopathybybeta receptorblockade. SwedbergK,WaagesteinF,HialmarsonA,etal. The Lancet . 1979