毒理芯片技术在药物毒理学中的应用

被引:13
作者
王全军
机构
[1] 军事医学科学院毒物药物研究所北京
关键词
毒理芯片; 毒理机制; 毒性预测;
D O I
10.13220/j.cnki.jipr.2003.02.012
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
近年来 ,生物芯片技术在生物学领域中得到了飞速的发展 ,并已开始用于药物毒理学领域 :包括基因芯片技术在药物毒理机制研究中的应用 ;发现毒理学中药物毒性的预测 ;化学物代谢特性分析与评价 ;化学致癌物筛选和识别 ,以及药物临床前安全性评价等。本文重点介绍了毒理芯片技术及其在药物毒理机制和药物毒性预测中的应用 ,并简单阐述了其在药物毒理上应用的局限性
引用
收藏
页码:110 / 113
页数:4
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