解偶联蛋白2与酒精性肝病

被引：2

作者：

王玮

周俊英

机构：

[1] 河北医科大学第三医院感染科

来源：

国际内科学杂志 | 2008年 / 05期

关键词：

解偶联蛋白2; 酒精性肝病; 氧化应激;

D O I：

暂无

中图分类号：

R575 [肝及胆疾病];

学科分类号：

100201 [内科学];

摘要：

解偶联蛋白2(UCP2)是线粒体内膜上可以调节质子跨膜转运的载体蛋白,可以驱散质子电化学梯度,使氧化呼吸与ATP合成解偶联。UCP2与能量消耗和脂质代谢密切相关,可能参与酒精性肝病(ALD)发病过程中的氧化应激和脂质过氧化。进一步探讨UCP2在ALD中的作用对于ALD的防治具有重要意义。

引用

页码：295 / 298

页数：4

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