卵巢肿瘤化疗耐药机制及逆转研究的进展

被引:4
作者
张殊
机构
[1] 上海第二医科大学附属仁济医院妇产科
关键词
卵巢肿瘤; 耐药; 基因; 细胞凋亡;
D O I
暂无
中图分类号
R737.31 [卵巢肿瘤];
学科分类号
100214 ;
摘要
研究表明许多参与肿瘤发生与发展的癌基因参与卵巢肿瘤对化疗药物产生耐药性,同时通过促细胞凋亡的方法可以增进肿瘤化疗的敏感性,就此详细阐述有关卵巢肿瘤化疗耐药及逆转的最新研究动态。
引用
收藏
页码:198 / 201
页数:4
相关论文
共 5 条
[1]  
A Novel Gene, CRR9, Which Was Up-Regulated in CDDP-Resistant Ovarian Tumor Cell Line, Was Associated with Apoptosis[J] . Kazue Yamamoto,Aikou Okamoto,Seiji Isonishi,Kazunori Ochiai,Yasuyuki Ohtake.Biochemical and Biophysical Research Communications . 2001 (4)
[2]  
Combination effect of adenovirus-mediated pro-apoptotic bax gene transfer with cisplatin or paclitaxel treatment in ovarian cancer cell lines[J] . Y Tsuruta,M Mandai,I Konishi,H Kuroda,T Kusakari,Y Yura,A.A Hamid,I Tamura,M Kariya,S Fujii.European Journal of Cancer . 2001 (4)
[3]   Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis [J].
Liu, JR ;
Fletcher, B ;
Page, C ;
Hu, C ;
Nunez, G ;
Baker, V .
GYNECOLOGIC ONCOLOGY, 1998, 70 (03) :398-403
[4]  
Role of p53 and apoptosis in sensitization of cis-diamminedichloroplatinumantitumor activity by interleukin-1 in ovarian carcinoma cells[J] . K Song,P Fukushima,P Seth,B K Sinha.International Journal of Oncology . 1998 (2)
[5]   Overexpression of the oncogene c-erbB-2 (HER2/neu) and response to chemotherapy in patients with ovarian cancer [J].
Meden, H ;
Marx, D ;
Roegglen, T ;
Schauer, A ;
Kuhn, W .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 1998, 17 (01) :61-65