多元耐药相关蛋白P170糖蛋白在白血病骨髓细胞中的表达

被引:4
作者
黄晓军
张海帆
王申五
薛文涛
机构
[1] 北京医科大学血液病研究所
[2] 北京医科大学血液病研究所 北京
[3] 北京
关键词
多元耐药性; P170糖蛋白; MKR16单克隆抗体; 白血病;
D O I
暂无
中图分类号
学科分类号
摘要
本文应用P170糖蛋白的单克隆抗体MRK16,采用流式细胞仪法对10例正常骨髓细胞和21例白血病骨髓细胞P170糖蛋白表达进行了测定。结果表明P170糖蛋白仅出现于白血病骨髓细胞,其中10例难治性白血病有7例阳性表达,11例初治性白血病仅3例阳性表达。这表明 P170糖蛋白与白血病相关,但 P170糖蛋白与白血病疗效的关系则尚待更大宗病例的进一步研究。
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页码:167 / 171
页数:5
相关论文
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