肿瘤介入性治疗副反应及并发症的防治

This article provides a review of complications and prevetion of interventional therapy of gynecologic tumors With the development of interventional radiology, interventional therapy plays an important role in the treatment of gynecologic tumors, and complications are hardly to be avoided The complications are as following:(1)complications caused by puncture and incubation: such as local haematoma in the site of puncture, thrombus in the lower limb and thrombosis, infection, injury of tunica intima, perforating the artery and catheter knot, etc All of those can be prevented by careful operation; (2)complications caused by contrast medium, it can cause allergy, hypersensitive dermal reaction, mild and severe systemic reaction All need to treat prudently and need corresponding management (3)complications associated with thrombus, such as fever, shedding of embolic agent and reflux, pain in buttocks nd paralysis of lower limbs, etc Patients should be carefully observed, and when those complications occurred it also needs corresponding management; Some patients with liver metastasis may undergo hepatic artery embolism therapy It can cause liver dysfunction, ascites, blood coagulation dysfunction, etc In patients with lung metastasis, it may be also necessary to undergo selective lung artary embolism Patients may occured cough,expectoration and coughing up blood When intercostal arteries are embolized, it will cause injury of spinal cord, but it is rare, numbness of the lower limbs, declination of myodynamia and disorders of defecation and miction will occure (4)complications associated with chemotherapeutic agents, all those agents have different degree adverse effect and toxicity to liver, kindey and bone marrow, they cause gastrointestinal tract discomfort and inhibition of bone marrow So blood, ECG, function of liver and kindey should be regularly monitored Additionally, they cause the region where agents perfused disorder of blood supply, dermal pigmentation and dermal necrosis All those complications mentioned above can be successfully managed if it can be prevented by sufficient pre operative prepareration and carefully post operative observation