狄诺塞麦治疗恶性肿瘤骨转移研究进展

被引：7

作者：

赵蔚

彭亚琪

任庆兰

机构：

[1] 重庆医科大学附属第一医院肿瘤科

来源：

重庆医学 | 2015年 / 44卷 / 16期

关键词：

骨肿瘤; 狄诺塞麦; RANK/RANKL/OPG轴;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 [肿瘤学];

摘要：

<正>骨是大部分实体肿瘤的常见转移部位,其中以乳腺癌及前列腺癌尤为常见[1-2]。恶性肿瘤骨转移可导致严重骨相关事件(skeletal related event,SRE)发生,SRE在病变局部表现为骨痛、病理性骨折、脊髓压缩性骨折,膀胱、直肠及生殖系统的功能障碍等,全身性改变包括高钙血症及肾衰竭等[2-3]。由此可见骨转移瘤所致的SRE严重影响患者的生活质

引用

页码：2276 / 2279

页数：4

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