糖尿病肾病的发病机制及治疗进展

被引：111

作者：

余翠 ^{[1
]}

熊钱颖 ^{[1
]}

王李卓 ^{[2
]}

高家林 ^{[1
]}

机构：

[1] 皖南医学院弋矶山医院内分泌科

[2] 皖南医学院生化教研室

来源：

医学综述 | 2015年 / 21卷 / 21期

关键词：

糖尿病肾病; 发病机制; 治疗;

D O I：

暂无

中图分类号：

R587.2 [糖尿病性昏迷及其他并发症];

学科分类号：

摘要：

糖尿病肾病发病机制复杂,遗传因素、高血糖、氧化应激、炎性反应及细胞因子等参与了其发生、发展。临床治疗包括控制血糖、控制血压、调节脂代谢等基础治疗,但疗效局限;针对发病机制的特异性治疗正在不断探索中,主要包括血管紧张素转换酶抑制剂、血管紧张素Ⅱ受体拮抗剂、他汀类、维生素D类似物、内皮素拮抗剂、晚期糖基化终末产物抑制剂、免疫抑制剂等多种药物。

引用

页码：3944 / 3947

页数：4

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