糖皮质激素和骨质疏松关系的研究进展

被引:19
作者
刘媛
王永福
刘忠厚
机构
[1] 包头医学院第一附属医院风湿免疫科
关键词
糖皮质激素; 骨质疏松; 骨折风险;
D O I
暂无
中图分类号
R580 [];
学科分类号
摘要
糖皮质激素(glucocorticoid,GC)具有良好而且独特的药理作用,临床应用非常广泛,有些患者需要长期使用。尽管GC的使用在很大程度上降低了许多炎症性疾病的发病率和死亡率,但是也伴随着许多负面效应。引起继发性骨质疏松症的病因很多,药物导致的骨质疏松症中最为常见的是糖皮质激素性骨质疏松症。骨质疏松也是GC引起的最严重副作用之一,易引起病理性骨折,致残率极高。因此,重视糖皮质激素引起的骨质疏松,积极地做出适当的评估很重要。本文通过论述糖皮质激素性骨质疏松的临床特征、发病机理、诊断、预防及治疗,以期为临床医生提供更为广泛的理论依据,得到更多的重视,并做出合理的评估和临床指导。
引用
收藏
页码:713 / 718
页数:6
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