软骨下骨在骨关节炎中的病理改变及其机制研究

被引：8

作者：

周荣

廖文洁

机构：

[1] 重庆市永川人民医院骨科

来源：

系统医学 | 2021年 / 6卷 / 24期

关键词：

软骨下骨; 骨关节炎; 病理改变; 机制; 研究进展;

D O I：

10.19368/j.cnki.2096-1782.2021.24.190

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

近些年以来,通过大量的研究证明,骨关节炎的发生以及进展和软骨下骨的改变具有密切关系。软骨下骨也已经被认为是治疗骨关节炎的一种潜力巨大的靶点。该文章从软骨下骨的结构以及功能入手,对骨关节炎软骨下骨的重塑进行研究,讨论骨关节炎软骨下骨组织学特征以及分级,分析软骨下骨转化生长因子β信号通路和骨关节炎的联系,阐述软骨下骨在骨关节炎中的病理性改变以及机制,进而为骨关节炎的治疗提供有力的治疗根据以及方向。

引用

页码：190 / 193

页数：4

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