苯二氮(艹卓)类在1954人中调查及药物不良反应

被引：10

作者：

耿晓芳

章正绪

黄雅琴

丁佩珍

机构：

[1] 华东医院内科神经科

[2] 上海市老年医学研究所临床药学室

来源：

中国临床药理学杂志 | 1991年 / 02期

关键词：

苯二氮(艹卓)类; 药物不良反应; 药物依赖性;

D O I：

10.13699/j.cnki.1001-6821.1991.02.016

中图分类号：

学科分类号：

摘要：

本文就有关苯二氮(艹卓)类的应用情况对1954人作了调研,结果表明:(1)服药率为33%,连续服药一年以上为25.55,(2)应用最多是安定,第二是三唑苯二氮(艹卓),(3)长期服药者容易产生药物不良反应,主要是药物依赖性及记忆力下降,老年人容易发生过度镇静,对呼吸功能不全的病人可引起严重的呼吸抑制,甚至死亡,(4)药物依赖性与年龄无明显相关,与服药的长期性及人格倾向有关。

引用

页码：119 / 123

页数：5

共 9 条

[1]

Biological basis for drug-indaeed tobance rebound and dependence. Haefely W. Pharmacopsychiatria . 1986

[2]

ADR Associated with global cognitive impairment in elderly persons. Larson EB,Kukull WA,Buchner D,Reifler BV,Washington S. Annals of Internal Medicine . 1987

[3]

Withdrawal reactive afterlong-term therapeutic use of benzodiazepins. Busto U,Pharm D,Sellers EM,et al. The New England Journal of Medicine . 1986

[4]

Risk of dependence on benzodiazepine drugs. Ashton H. British Medical Journal . 1989

[5]

Risk of dependence on benzodiazepine drugs. Ashton H. British Medical Journal . 1989

[6]

Toxicity of flurazepam of heavy dose in elderly persons. Greeblatt DJ,Alen MD,Shader RI. Clinical Pharmacology and Therapeutics . 1977

[7]

Long term diazepine therapy and clinical caterce. Rickels K,Case WG,Downing Rw,Winokur A. The Journal of The American Medical Association . 1983

[8]

Benzodiazepine withdrawal: Overview and implicatine of treatment of anxiety. Roy-Byrne PP,Hommer D. The American Journal of Medicine . 1988

[9]

Benzodiazepines dependince: Arevises of evidance. Owen RT,Tyrer P. Drugs . 1983

← 1 →