坏死性凋亡在乙醇诱导肝损伤机制中的作用研究进展

被引：2

作者：

杨海玉 ^{[1
]}

刘勇 ^{[2
]}

机构：

[1] 江西省人民医院临床医学研究所

[2] 江西省人民医院病理科

来源：

南昌大学学报(医学版) | 2016年 / 56卷 / 04期

关键词：

坏死性凋亡; 乙醇滥用; 乙醇性肝病; 肝损伤; 机制;

D O I：

10.13764/j.cnki.ncdm.2016.04.024

中图分类号：

R575 [肝及胆疾病];

学科分类号：

100201 [内科学];

摘要：

<正>乙醇滥用是目前全球关注的医学和社会问题。肝脏是机体重要的代谢器官,对体内外许多物质(药物、毒物及某些代谢产物等)具有生物转化作用。乙醇在肝脏代谢中氧化为乙醛、乙酸,其代谢产物是诱导肝损伤的主要因素。长期乙醇暴露可导致明显的肝损伤和组织重建,包括肝脂肪变性、肝炎、肝纤维化、肝硬化等病理改变,通常称之为乙醇性肝病,该

引用

页码：98 / 100

页数：3

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