Notch信号通路在肿瘤治疗中的研究进展

被引：4

作者：

刘尚文

张旭

机构：

[1] 解放军总医院泌尿外科

来源：

实用医学杂志 | 2011年 / 27卷 / 19期

关键词：

信号通路; 肿瘤细胞; Notch; 肿瘤治疗; 肿瘤干细胞; 肿瘤抗药性;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 ;

摘要：

<正>跨膜受体蛋白Notch信号通路的活性在决定细胞命运(包括增殖、分化以及凋亡)过程中发挥着重要作用,它的功能异常将导致未分化细胞向肿瘤细胞转化。人类许多肿瘤中均可检测到Notch信号通路活性的改变,并且

引用

页码：3609 / 3611

页数：3

共 12 条

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