高含量β-胡萝卜素微胶囊干粉流动性的考察及其影响因素(英文)

被引:11
作者
许新德 [1 ]
姚善泾 [1 ]
韩宁 [1 ]
邵斌 [2 ]
机构
[1] Department of Chemical and Biochemical Engineering,Zhejiang University
[2] Xinchang PharmaFactory,Zhejiang Medical CoLtd
关键词
β-carotene; microcapsule powders; flowability; Hausner ratio; repose angle;
D O I
暂无
中图分类号
TS201 [基础科学];
学科分类号
083201 ;
摘要
The flowability of five kinds of microencapsulation powders,with differentβ-carotene contents and by two alternative particle-forming technologies i.e.spray-drying and starch-catching beadlet technology,was meas- ured.The actual flow properties of the five powders were compared based on bin-flow test,and three flow indexes (Hausner ratio,repose angle and flow index)were measured.It was found that the repose angle is the most suitable index to reflect the flowability of these powders for the particle properties would not be altered due to compaction or tapping during the measuring process.Particle size and particle size distribution play most important roles in the flowability of these granular materials,which was also influenced by other factors like shape,surface texture,sur- face roughness,etc.Microcapsules with wall material of gelatin and a layer of modified starch absorbed on the sur- face showed excellent flowabilities and good mechanical properties,and they are favorable for tabletting to supply β-carotene.
引用
收藏
页码:579 / 585
页数:7
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