冠状动脉造影患者心血管病危险因素与冠状动脉病变程度的相关性分析

被引：64

作者：

郭永和

张维君

周玉杰

赵冬

周志明

张红

机构：

[1] 首都医科大学附属北京安贞医院心内科,首都医科大学附属北京安贞医院心内科,首都医科大学附属北京安贞医院心内科,首都医科大学附属北京安贞医院心内科,首都医科大学附属北京安贞医院心内科,首都医科大学附属北京安贞医院心内科,,,,,

来源：

中华心血管病杂志 | 2005年 / 05期

关键词：

冠状动脉疾病; 冠状血管造影术; 危险因素;

D O I：

暂无

中图分类号：

R543.3 [冠状动、静脉疾病];

学科分类号：

摘要：

目的探讨心血管疾病危险因素与冠状动脉造影病变程度相关性。方法入选行冠状动脉造影住院病例920例,其中确诊冠心病患者728例(占79.13%),排除冠心病患者192例(占20.87%)。冠状动脉造影病变程度由病变支数,经造影是否诊断冠心病及病变Gensini总积分表示。危险因素包括性别、年龄、高血压病、吸烟、2型糖尿病、血脂异常、高尿酸。采用单因素和多因素分析。结果(1)单因素分析显示,在病变程度不同的各组间比较,随各组中存在单个危险因素病例百分率的增加,冠状动脉造影病变支数和病变Gensini总积分随之增加。(2)多因素Logistic回归分析(前进法)显示,高LDL C为冠状动脉造影诊断冠心病最显著的独立相关危险因素(OR=2.816,95%可信区间1.903,4.167,P=0.001),其他危险因素依次为男性、吸烟、2型糖尿病、低HDL C、高血压病、高尿酸血症和增龄。性别分组后分别经多因素Logistic回归(前进法)分析显示,男性组中高LDL C为冠状动脉造影诊断冠心病最显著的独立相关的危险因素(OR=2.965,95%可信区间1.880,4.676,P=0.009)。女性分组中吸烟(OR=2.840,95%可信区间0.553,5.378,P=0.001)和高尿酸血症(OR=2.132,95%可信区间1.048,3.641,P=0.017)为冠状动脉造影诊断冠心病最显著的独立相关的危险因素。结论高LDL C是冠状动脉造影

引用

页码：415 / 418

页数：4

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