颈动脉双向流固耦合模型非稳态血流数值分析

被引：19

作者：

刘莹 ^{[1
]}

章德发 ^{[1
]}

殷艳飞 ^{[1
]}

张智亮 ^{[2
]}

机构：

[1] 南昌大学机电工程学院

[2] 南昌大学第一附属医院心血管科

来源：

介入放射学杂志 | 2015年 / 24卷 / 10期

关键词：

流固耦合; 颈动脉; 粥样斑块; 心动周期; 血流动力学;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

目的研究流固耦合作用下颈动脉内一个心动周期典型时刻血流动力学分布,探索颈动脉粥样斑块形成与发展机制。方法采用计算流体力学方法对一个心动周期颈动脉内血流特性进行数值分析,根据血流动力学特征参数分析心动收缩期和心动舒张期对血流分布特性的影响。结果获得一个心动周期典型时刻颈动脉内血流特性分布情况。与心动舒张期相比,心动收缩期颈外动脉入口处分布较大面积血流停滞区,该区域内血流速度低,壁面压力低,壁面切应力低,管壁形变量和von Mises等效应力较大。结论流固耦合作用下颈动脉血流速度低引起血液回流,脂质、纤维等大分子易沉积;壁面压力低形成"负压"效应,正常血流发生改变,流动速度变慢,脑部供血不足;壁面切应力低使近壁面血流流态被破坏,血小板活性增强,内膜过度增生;管壁形变量和von Mises等效应力较大易引起应力集中,增大血管破裂风险。

引用

页码：885 / 889

页数：5

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