槲皮素在治疗骨关节炎中作用机制的研究进展

被引：54

作者：

于维汉

何耀华

机构：

[1] 上海交通大学附属第六人民医院运动医学科

来源：

中华骨与关节外科杂志 | 2019年 / 12卷 / 06期

关键词：

槲皮素; 骨关节炎; 促炎性细胞因子; 细胞外基质;

D O I：

暂无

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

骨关节炎(OA)是一种临床常见疾病,严重影响患者生活。OA发病机制尚未明确,主要原因包括促炎性细胞因子增多、炎症相关信号通路激活、细胞外基质降解等。槲皮素是一种天然黄酮类化合物,广泛存在于蔬菜水果当中。槲皮素可减少促炎性细胞因子生成、调控炎症相关信号通路,抑制细胞外基质降解,具有治疗OA的潜在药物价值。本文就近年来槲皮素治疗OA作用机制方面的研究进展做一综述。

引用

页码：477 / 480

页数：4

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