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Development of a protein-free medium with iron salts replacing transferrin for a human-human hybridoma. Nagira K,Hara T,Hayashida M,et al. Bioscience Biotechnology and Biochemistry . 1995
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In hybridoma cultures,deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene. Simpson NH,Singh RP.Perani A,et al. Biotechnology and Bioengineering . 1998
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The pro in hydrolysate, Primatone RL.is a cost-effective multiple growth promoter of mammalian cell culture in serum-containing and serum-free media and displays anti-apoptosis properties. Schlaeger EJ. Journal of Immunological Methods . 1996
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Avoiding rapid growth at high cell densities: A potentially important optimisation criterion for hybridoma cultures[J] . L. K. Nielsen,W. Niloperbowo,S. Reid,P. F. Greenfield.  Cytotechnology . 1992 (1)
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