控制2型糖尿病,利拉鲁肽尽早应用的益处

被引：12

作者：

高妍

机构：

[1] 北京大学第一医院内分泌科

来源：

中国糖尿病杂志 | 2012年 / 20卷 / 12期

关键词：

糖尿病,2型; 利拉鲁肽; 胰岛细胞; 肠促胰素; 药物经济学;

D O I：

暂无

中图分类号：

R587.1 [糖尿病];

学科分类号：

100201 [内科学];

摘要：

在T2DM的发生发展过程中,胰岛α细胞和β细胞存在结构和数量异常、功能障碍。胰升血糖素样肽-1(GLP-1)类似物利拉鲁肽可直接改善胰岛β细胞功能、抑制其凋亡和增加其数量,并能作用于胰岛α细胞,不仅能够调节细胞功能,早期应用于T2DM治疗有效改善血糖,减少低血糖发生率,还能带来降低体重、SBP的益处,其具有药物经济学优势,是T2DM早期治疗的理想选择。

引用

收藏

页码：954 / 957

页数：4

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