1,3-二炔类天然产物的合成及生物活性研究进展

被引：8

作者：

苗延红 ^{[1
,2
]}

马开庆 ^{[1
]}

秦雪梅 ^{[1
]}

机构：

[1] 山西大学中医药现代研究中心

[2] 山西大学化学化工学院

来源：

天然产物研究与开发 | 2017年 / 29卷 / 09期

关键词：

1,3-二炔类天然产物; 有机合成; 生物活性; 毒性;

D O I：

10.16333/j.1001-6880.2017.9.026

中图分类号：

R284 [中药化学];

学科分类号：

100804 [中药化学];

摘要：

多炔类化合物是广泛存在于自然界的一类天然产物,由于其独特的结构和药理活性,近年来引起了国内外化学家和生物学家的广泛关注。目前多炔类天然产物的研究多集中于1,3-二炔类化合物,该类天然产物具有多样性的结构和生物活性如抗癌、神经毒性、抗炎活性、免疫抑制活性等,但相关进展综述迄今尚未见报道。本文系统的综述了近年国内外对1,3-二炔类天然产物的合成及药理活性研究进展,以期为1,3-二炔类天然产物的开发和利用提供思路和方法。

引用

页码：1608 / 1616

页数：9

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