地氟醚与七氟醚麻醉对老年病人术后认知功能的影响

被引：50

作者：

陈晓光

王俊科

王淑月

机构：

[1] 中国医科大学附属第一医院

[2] 河北医科大学药学院

来源：

中华麻醉学杂志 | 2002年 / 04期

关键词：

老年人; 认知障碍; 地氟醚; 七氟醚;

D O I：

暂无

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

目的探讨地氟醚及七氟醚复合麻醉对老年病人术后认知功能恢复的影响。方法 70例择期行全膝或全髋关节置换术的病人,年龄均在65岁以上。静注芬太尼、异丙酚、琥珀胆碱快速诱导插管后随机分为地氟醚和异氟醚组。麻醉诱导前及手术后1、3、6及24h应用Mini-Mental State（MMS）测试方法评定其认知功能。结果与术前相比,两组病人术后1h MMS值均明显降低。地氟醚组由29.5±0.5降至27.8±1.7;七氟醚组由29.2±1.0降至27.4±1.7。其中85％以上病人术后3h MMS恢复至术前水平。两组病人术前及术后1、3、6及24h MMS比较均无显著差异。结论老年病人应用地氟醚或七氟醚麻醉,其术后认知功能恢复相似,仅有一过性认知障碍。

引用

页码：21 / 23

页数：3

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